NON PCR-AMPLIFIED TRANSCRIPTS AND AFLP FRAGMENTS AS REDUCED REPRESENTATIONS OF THE QUAIL GENOME FOR 454 TITANIUM SEQUENCING

Non PCR-amplified Transcripts and AFLP fragments as reduced representations of the quail genome for 454 Titanium sequencing

Abstract Background SNP (Single Nucleotide Polymorphism) discovery Travel Mugs is now routinely performed using high-throughput sequencing of reduced representation libraries.Our objective was to adapt 454 GS FLX based sequencing methodologies in order to obtain the largest possible dataset from two reduced representations libraries, produced by AF

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Investigation of characteristic hemodynamic parameters indicating thinning and thickening sites of cerebral aneurysms

Cellular and animal experiments and computational fluid dynamics (CFD) have revealed that mechanisms of the initiation, growth and rupture of a cerebral aneurysm are related to hemodynamics.By direct observation of a cerebral aneurysm during craniotomy, thinning or thickening sites can be found on the aneurysmal wall.The thinning site of a cerebral

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Exploring Research Culture in Care Homes to Identify the Barriers and Facilitators to Research: A Rapid Review

Context: There are more than 400,000 people living in just over 17,000 care homes in the UK.Nevertheless, the quantity of care home research taking place in these settings is limited.This has led to a knowledge gap that impacts on care home practices, resident health outcomes, and the development of policy.Objectives: The objective of this rapid re

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